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Group:

Reptile

Estimated genome size:

10 - 20 cm (total body length)

Size:

10 - 20 cm (total body length)

Distribution:

Endemic to the Republic of South Africa, occurring in Little Namaqualand from Port Nolloth to Clanwilliam.

PromethION Sequencing Report:

Output:

48.66 Gigabases

Approximate N50:

5.93 kilobases

Draft Genome Assembly Statistics:

Genome Length:

1.56 Gigabases

BUSCO completeness score (single and duplicated genes):

98.8% [S: 96.9%, D: 2.0%]

Importance:

It serves as an important model species for studying specific stages of limb development within the genus Scelotes, representing an intermediate limb development stage (forelimb digits = 0; hindlimb digits = 2), and for investigating the genomic evolution of vertebrates. It has a restricted distribution and occurs in distinct habitats and regions, making it an excellent model species for biogeographic and molecular ecology studies.

Sample Contributor contact details:

Dr. Zhongning Zhao
University of Free State

Group:

Eudicot

Genome size:

991 million DNA base pairs (0.99 Gigabases)

Size:

0.5 – 1 meter in height

Distribution:

Lessertia frutescens occurs naturally throughout the dry parts of southern Africa – in Western Cape and up the west coast as far north as Namibia and into Botswana, and in the western Karoo to Eastern Cape. It is also found in KwaZulu-Natal and Mpumalanga. It shows remarkable variation within its distribution

PromethION Sequencing Report:

Output:

225.29 Gigabases

Approximate N50:

1.74 kilobases

Assembly N50:

TBA

Contig number:

TBA

Draft Genome Assembly Statistics:

Assembler used:

TBA

Genome Length:

0.45 Gigabases

BUSCO completeness score (single and duplicated genes):

94.3% [S: 90.8%, D: 3.5%]

BUSCO database:

TBA

Lessertia frutescens

Cancer bush

Species Card Details

Importance:

This plant is one of the most discussed in the ethnobotanical world because it has a strong reputation as a cure for cancer and increasingly as an immune booster in the treatment of HIV/AIDS. It has long been known, used and respected as a medicinal plant in southern Africa. There is preliminary clinical evidence that it has a direct anti-cancer effect in some cancers and that it acts as an immune stimulant. Research on its properties is ongoing.

Sample Contributor contact details:

Thabang Makola
South African National Biodiversity Institute

Date Published:

2025-03-12

Awaiting DOI

Photo credit:

© T. Makola

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